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Symbol
Name
ID
Trem2
triggering receptor expressed on myeloid cells 2
MGI:1913150
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
increased macrophage apoptosis
decreased macrophage proliferation
impaired macrophage phagocytosis
decreased macrophage cell number
abnormal microglial cell physiology
decreased microglial cell activation
increased circulating interleukin-6 level
increased circulating tumor necrosis factor level
abnormal interferon level
abnormal interleukin level
abnormal tumor necrosis factor level
increased susceptibility to endotoxin shock
Availability Mouse Genotype
Trem2em2Bwef/Trem2em2Bwef
Trem2tm1(KOMP)Vlcg/Trem2tm1(KOMP)Vlcg
Trem2tm1Cln/Trem2tm1Cln
Trem2em2Bwef/Trem2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory